Carpal tunnel syndrome is a condition where pressure on one of the main nerves to the hand (the Median nerve) leads to uncomfortable pins and needles sensations in the hand and, in the more severe cases, numbness, muscle wasting and weakness in the hand.
The nerve passes through a tunnel in the wrist that has a bony floor and sides but the roof of the tunnel is formed by a strong ligament (the transverse carpal ligament).